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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLK1
All Species:
20
Human Site:
T111
Identified Species:
44
UniProt:
Q9UKI8
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKI8
NP_036422.3
766
86700
T111
L
S
D
K
E
S
E
T
P
E
K
K
Q
S
E
Chimpanzee
Pan troglodytes
XP_001141231
787
89005
T111
L
S
D
K
E
S
E
T
P
E
K
K
Q
S
E
Rhesus Macaque
Macaca mulatta
XP_001084145
718
81923
S111
Y
Q
G
G
N
G
S
S
P
V
R
G
I
P
P
Dog
Lupus familis
XP_535959
766
86670
T111
L
S
D
K
E
S
E
T
P
E
K
K
Q
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0V0
766
86605
T111
L
S
D
K
E
S
E
T
P
E
K
K
Q
S
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515053
718
81881
S111
Y
Q
G
G
N
G
S
S
P
V
R
G
I
P
P
Chicken
Gallus gallus
XP_426581
764
86358
T112
L
S
D
K
E
S
E
T
P
E
K
K
Q
S
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q90ZY6
756
85436
E112
D
K
E
S
E
T
P
E
K
K
H
F
E
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624065
793
90042
R139
H
L
G
N
S
P
I
R
H
G
G
A
K
S
P
Nematode Worm
Caenorhab. elegans
P34314
965
109255
Q156
H
P
H
Q
M
Q
M
Q
Q
Q
Q
Q
H
H
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39238
688
78131
D111
S
N
N
F
S
V
V
D
H
V
E
P
Q
E
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
93.5
99.4
N.A.
98.1
N.A.
N.A.
91.5
94.1
N.A.
83.2
N.A.
N.A.
46.4
37.9
N.A.
Protein Similarity:
100
97.3
93.7
99.7
N.A.
99.2
N.A.
N.A.
92.8
95.8
N.A.
89.4
N.A.
N.A.
61.2
50.8
N.A.
P-Site Identity:
100
100
6.6
93.3
N.A.
100
N.A.
N.A.
6.6
100
N.A.
13.3
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
100
100
20
100
N.A.
100
N.A.
N.A.
20
100
N.A.
40
N.A.
N.A.
13.3
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
46
0
0
0
0
10
0
0
0
0
0
0
10
% D
% Glu:
0
0
10
0
55
0
46
10
0
46
10
0
10
10
37
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
28
19
0
19
0
0
0
10
10
19
0
0
0
% G
% His:
19
0
10
0
0
0
0
0
19
0
10
0
10
10
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
19
0
0
% I
% Lys:
0
10
0
46
0
0
0
0
10
10
46
46
10
0
0
% K
% Leu:
46
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
10
10
19
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
10
10
0
64
0
0
10
0
19
28
% P
% Gln:
0
19
0
10
0
10
0
10
10
10
10
10
55
0
10
% Q
% Arg:
0
0
0
0
0
0
0
10
0
0
19
0
0
0
0
% R
% Ser:
10
46
0
10
19
46
19
19
0
0
0
0
0
64
10
% S
% Thr:
0
0
0
0
0
10
0
46
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
10
0
0
28
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _